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Chromosome segregation and organization are targets of 5′-Fluorouracil in eukaryotic cells
The antimetabolite 5′-Fluorouracil (5FU) is an analog of uracil commonly employed as a chemotherapeutic agent in the treatment of a range of cancers including colorectal tumors. To assess the cellular effects of 5FU, we performed a genome-wide screening of the haploid deletion library of the eukaryo...
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| Veröffentlicht in: | Cell Cycle |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352961/ https://ncbi.nlm.nih.gov/pubmed/25483073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.974425 |
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