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Chromosome segregation and organization are targets of 5′-Fluorouracil in eukaryotic cells

The antimetabolite 5′-Fluorouracil (5FU) is an analog of uracil commonly employed as a chemotherapeutic agent in the treatment of a range of cancers including colorectal tumors. To assess the cellular effects of 5FU, we performed a genome-wide screening of the haploid deletion library of the eukaryo...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Mojardín, Laura, Botet, Javier, Moreno, Sergio, Salas, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352961/
https://ncbi.nlm.nih.gov/pubmed/25483073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.974425
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