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EF-hand protein Ca(2+) buffers regulate Ca(2+) influx and exocytosis in sensory hair cells

EF-hand Ca(2+)-binding proteins are thought to shape the spatiotemporal properties of cellular Ca(2+) signaling and are prominently expressed in sensory hair cells in the ear. Here, we combined genetic disruption of parvalbumin-α, calbindin-D28k, and calretinin in mice with patch-clamp recording, in...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pangršič, Tina, Gabrielaitis, Mantas, Michanski, Susann, Schwaller, Beat, Wolf, Fred, Strenzke, Nicola, Moser, Tobias
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352837/
https://ncbi.nlm.nih.gov/pubmed/25691754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416424112
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