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Autocrine prostaglandin E(2) signaling promotes promonocytic leukemia cell survival via COX-2 expression and MAPK pathway
The COX-2/PGE(2) pathway has been implicated in the occurrence and progression of cancer. The underlying mechanisms facilitating the production of COX-2 and its mediator, PGE(2), in cancer survival remain unknown. Herein, we investigated PGE(2)-induced COX-2 expression and signaling in HL-60 cells f...
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| Publié dans: | BMB Rep |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Korean Society for Biochemistry and Molecular Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352612/ https://ncbi.nlm.nih.gov/pubmed/24965577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.2.081 |
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