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The Allosteric Binding Sites of Sulfotransferase 1A1

Human sulfotransferases (SULTs) comprise a small, 13-member enzyme family that regulates the activities of thousands of compounds—endogenous metabolites, drugs, and other xenobiotics. SULTs transfer the sulfuryl-moiety (–SO(3)) from a nucleotide donor, PAPS (3′-phosphoadenosine 5′-phosphosulfate), t...

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Publicado en:Drug Metab Dispos
Autores principales: Cook, Ian, Wang, Ting, Falany, Charles N., Leyh, Thomas S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352582/
https://ncbi.nlm.nih.gov/pubmed/25534770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.061887
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