Spleen tyrosine kinase contributes to acute renal allograft rejection in the rat

Kidney allografts induce strong T-cell and antibody responses which mediate acute rejection. Spleen tyrosine kinase (Syk) is expressed by most leucocytes, except mature T cells, and is involved in intracellular signalling following activation of the Fcγ-receptor, B-cell receptor and some integrins....

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Bibliographic Details
Published in:Int J Exp Pathol
Main Authors: Ramessur Chandran, Sharmila, Tesch, Greg H, Han, Yingjie, Woodman, Naomi, Mulley, William R, Kanellis, John, Blease, Kate, Ma, Frank Y, Nikolic-Paterson, David J
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352352/
https://ncbi.nlm.nih.gov/pubmed/25529862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12110
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