C6 Produced by Macrophages Contributes to Cardiac Allograft Rejection

The terminal components of complement C5b-C9 can cause significant injury to cardiac allografts. Using C6-deficient rats, we have found that the rejection of major histocompatibility (MHC) class I-incompatible PVG.R8 (RT1.A(a)B(u)) cardiac allografts by PVG.1U (RT1.A(u)B(u)) recipients is particular...

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Main Authors: Qian, Zhiping, Wasowska, Barbara A., Behrens, Edward, Cangello, David L., Brody, Jonathan R., Kadkol, ShriHari S., Horwitz, Louis, Liu, Jinhuan, Lowenstein, Charles, Hess, Allan D., Sanfilippo, Fred, Baldwin, William M.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867035/
https://ncbi.nlm.nih.gov/pubmed/10514411
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