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Enhancing The Bystander Killing Effect Of An Oncolytic HSV By Arming It With A Secretable Apoptosis Activator

Although oncolytic viruses have shown great promise as cancer therapeutics, results from a recent phase III clinical trial indicate that their potency may need further improvement for a clear clinical benefit. Here, we report a novel strategy to increase the bystander effect of virotherapy by arming...

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Bibliografiske detaljer
Udgivet i:Gene Ther
Main Authors: Loya, Shana Marie Williamson, Zhang, Xiaoliu
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352111/
https://ncbi.nlm.nih.gov/pubmed/25567538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.113
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