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Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis

Breast cancer metastasis involves lymphatic dissemination in addition to hematogenous spreading. Although stromal lymphatic vessels (LVs) serve as initial metastatic routes, roles of organ-residing LVs are under-investigated. Here we show that lymphatic endothelial cells (LECs), a component of LVs w...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Esak, Fertig, Elana J., Jin, Kideok, Sukumar, Saraswati, Pandey, Niranjan B., Popel, Aleksander S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351998/
https://ncbi.nlm.nih.gov/pubmed/25178650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5715
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