Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells

Adverse side effects and acquired resistance to conventional platinum based chemotherapy have become major impediments in ovarian cancer treatment, and drive the development of more selective anticancer drugs. Chaetoglobosin K (ChK) was shown to have a more potent growth inhibitory effect than cispl...

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Publicado en:Cancer Lett
Main Authors: Li, Bo, Gao, Ying, Rankin, Gary O., Rojanasakul, Yon, Cutler, Stephen J., Tu, Youying, Chen, Yi Charlie
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351971/
https://ncbi.nlm.nih.gov/pubmed/25304379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.023
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