Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells

Adverse side effects and acquired resistance to conventional platinum based chemotherapy have become major impediments in ovarian cancer treatment, and drive the development of more selective anticancer drugs. Chaetoglobosin K (ChK) was shown to have a more potent growth inhibitory effect than cispl...

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Bibliografiska uppgifter
I publikationen:Cancer Lett
Huvudupphovsmän: Li, Bo, Gao, Ying, Rankin, Gary O., Rojanasakul, Yon, Cutler, Stephen J., Tu, Youying, Chen, Yi Charlie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351971/
https://ncbi.nlm.nih.gov/pubmed/25304379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.09.023
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