Recombinant NAD-dependent SIR-2 Protein of Leishmania donovani: Immunobiochemical Characterization as a Potential Vaccine against Visceral Leishmaniasis

BACKGROUND: The development of a vaccine conferring long-lasting immunity remains a challenge against visceral leishmaniasis (VL). Immunoproteomic characterization of Leishmania donovani proteins led to the identification of a novel protein NAD+-dependent Silent Information regulatory-2 (SIR2 family...

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Pubblicato in:PLoS Negl Trop Dis
Autori principali: Baharia, Rajendra K, Tandon, Rati, Sharma, Tanuj, Suthar, Manish K, Das, Sanchita, Siddiqi, Mohammad Imran, Saxena, Jitendra Kumar, Sunder, Shyam, Dube, Anuradha
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351947/
https://ncbi.nlm.nih.gov/pubmed/25745863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003557
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