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Protection against Streptococcus pneumoniae lung infection after nasopharyngeal colonization requires both humoral and cellular immune responses

Streptococcus pneumoniae is a common cause of pneumonia and infective exacerbations of chronic lung disease, yet there are few data on how adaptive immunity can specifically prevent S. pneumoniae lung infection. We have used a murine model of nasopharyngeal colonization by the serotype 19F S. pneumo...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Wilson, R, Cohen, J M, Jose, R J, de Vogel, C, Baxendale, H, Brown, J S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351900/
https://ncbi.nlm.nih.gov/pubmed/25354319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.95
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