Immunization with Recombinant Streptococcus pneumoniae Neuraminidase NanA Protects Chinchillas against Nasopharyngeal Colonization

Immunization with recombinant S. pneumoniae neuraminidase NanA (rNanA) resulted in a significant reduction in pneumococcal colonization in the chinchilla model. The bacteria were eliminated from the nasopharynx 1 week earlier than that from the control cohort. Our data suggest that rNanA affords pro...

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Detalhes bibliográficos
Main Authors: Tong, H. H., Li, D., Chen, S., Long, J. P., DeMaria, T. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1273864/
https://ncbi.nlm.nih.gov/pubmed/16239584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.11.7775-7778.2005
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