Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors

Mammals express the sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV). Neu5Gc is synthesized from Neu5Ac by the enzyme cytidine monophosphate-N-acetylneuraminic acid hydr...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Ng, Preston S.K., Böhm, Raphael, Hartley-Tassell, Lauren E., Steen, Jason A., Wang, Hui, Lukowski, Samuel W., Hawthorne, Paula L., Trezise, Ann E.O., Coloe, Peter J., Grimmond, Sean M., Haselhorst, Thomas, von Itzstein, Mark, Paton, Adrienne W., Paton, James C., Jennings, Michael P.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351649/
https://ncbi.nlm.nih.gov/pubmed/25517696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6750
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