Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling

Hypertension induces structural remodelling of arteries, which leads to arteriosclerosis and end-organ damage. Hyperplasia of vascular smooth muscle cells (VSMCs) and infiltration of immune cells are the hallmark of hypertensive arterial remodelling. However, the precise molecular mechanisms of arte...

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Publicat a:Nat Commun
Autors principals: Sumida, Tomokazu, Naito, Atsuhiko T., Nomura, Seitaro, Nakagawa, Akito, Higo, Tomoaki, Hashimoto, Akihito, Okada, Katsuki, Sakai, Taku, Ito, Masamichi, Yamaguchi, Toshihiro, Oka, Toru, Akazawa, Hiroshi, Lee, Jong-Kook, Minamino, Tohru, Offermanns, Stefan, Noda, Tetsuo, Botto, Marina, Kobayashi, Yoshio, Morita, Hiroyuki, Manabe, Ichiro, Nagai, Toshio, Shiojima, Ichiro, Komuro, Issei
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351572/
https://ncbi.nlm.nih.gov/pubmed/25716000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7241
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