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Defective platelet autocrine signaling in HPS
In this issue of Blood, Meng et al(1) and Sharda et al(2) use the Hermansky-Pudlak syndrome (HPS) as a model to show that adenosine 5′-diphosphate (ADP) released by dense granules serves as an autocrine signal to potentiate platelet release of α-granule and lysosome cargo and protein disulfide isome...
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| Published in: | Blood |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351501/ https://ncbi.nlm.nih.gov/pubmed/25745182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-616284 |
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