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Defective platelet autocrine signaling in HPS

In this issue of Blood, Meng et al(1) and Sharda et al(2) use the Hermansky-Pudlak syndrome (HPS) as a model to show that adenosine 5′-diphosphate (ADP) released by dense granules serves as an autocrine signal to potentiate platelet release of α-granule and lysosome cargo and protein disulfide isome...

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Bibliografiske detaljer
Udgivet i:Blood
Hovedforfatter: Storrie, Brian
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351501/
https://ncbi.nlm.nih.gov/pubmed/25745182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-616284
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