A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1

AIMS/HYPOTHESIS: Intronic single nucleotide polymorphisms (SNPs) in the CDKAL1 gene are associated with risk of developing type 2 diabetes. A strong correlation between risk alleles and lower levels of the non-coding RNA, CDKAL1-v1, has recently been reported in whole blood extracted from Japanese i...

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Опубликовано в: :Diabetologia
Главные авторы: Locke, Jonathan M., Wei, Fan-Yan, Tomizawa, Kazuhito, Weedon, Michael N., Harries, Lorna W.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2015
Предметы:
Short Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351432/
https://ncbi.nlm.nih.gov/pubmed/25634229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3508-9
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