Loading...

Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes

Fibroblast growth factor receptor 3 (FGFR3) plays a critical role in the control of endochondral ossification, and bone growth and mutations that cause hyperactivation of FGFR3 are responsible for a collection of developmental disorders that feature poor endochondral bone growth. FGFR3 is expressed...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Zhou, Zi-Qiang, Ota, Sara, Deng, Chuxia, Akiyama, Haruhiko, Hurlin, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351382/
https://ncbi.nlm.nih.gov/pubmed/25432534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu594
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!