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Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of Three Population-Based Cohorts

BACKGROUND: High-throughput profiling of circulating metabolites may improve cardiovascular risk prediction over established risk factors. METHODS AND RESULTS: We applied quantitative NMR metabolomics to identify biomarkers for incident cardiovascular disease during long-term follow-up. Biomarker di...

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Bibliographic Details
Published in:Circulation
Main Authors: Würtz, Peter, Havulinna, Aki S, Soininen, Pasi, Tynkkynen, Tuulia, Prieto-Merino, David, Tillin, Therese, Ghorbani, Anahita, Artati, Anna, Wang, Qin, Tiainen, Mika, Kangas, Antti J, Kettunen, Johannes, Kaikkonen, Jari, Mikkilä, Vera, Jula, Antti, Kähönen, Mika, Lehtimäki, Terho, Lawlor, Debbie A, Gaunt, Tom R, Hughes, Alun D, Sattar, Naveed, Illig, Thomas, Adamski, Jerzy, Wang, Thomas J, Perola, Markus, Ripatti, Samuli, Vasan, Ramachandran S, Raitakari, Olli T, Gerszten, Robert E, Casas, Juan-Pablo, Chaturvedi, Nish, Ala-Korpela, Mika, Salomaa, Veikko
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351161/
https://ncbi.nlm.nih.gov/pubmed/25573147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.013116
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