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Selective inhibitors of nuclear export (SINE) in hematological malignancies
Regulated nucleo-cytoplasmic transport plays a major role in maintaining cellular homeostasis. CRM1 (chromosome region maintenance 1 or exportin 1 or XPO 1) is responsible for the nucleo-cytoplasmic transport of more than 200 proteins, including most of the tumor suppressor proteins (TSP). CRM1 is o...
Sparad:
| I publikationen: | Exp Hematol Oncol |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BioMed Central
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350974/ https://ncbi.nlm.nih.gov/pubmed/25745591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-015-0002-5 |
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