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Charge Reduction and Thermodynamic Stabilization of Substrate RNAs Inhibit RNA Editing
African trypanosomes cause a parasitic disease known as sleeping sickness. Mitochondrial transcript maturation in these organisms requires a RNA editing reaction that is characterized by the insertion and deletion of U-nucleotides into otherwise non-functional mRNAs. Editing represents an ideal targ...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350841/ https://ncbi.nlm.nih.gov/pubmed/25742417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118940 |
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