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Charge Reduction and Thermodynamic Stabilization of Substrate RNAs Inhibit RNA Editing

African trypanosomes cause a parasitic disease known as sleeping sickness. Mitochondrial transcript maturation in these organisms requires a RNA editing reaction that is characterized by the insertion and deletion of U-nucleotides into otherwise non-functional mRNAs. Editing represents an ideal targ...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Leeder, W.-Matthias, Reuss, Andreas J., Brecht, Michael, Kratz, Katja, Wachtveitl, Josef, Göringer, H. Ulrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350841/
https://ncbi.nlm.nih.gov/pubmed/25742417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118940
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