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A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice

We have previously observed that Wnt signaling activates a fibrogenic program in adult muscle stem cells, called satellite cells, during aging. We genetically labeled satellite cells in a mouse model of Duchenne muscular dystrophy to follow their fate during the progression of the disease. We observ...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Biressi, Stefano, Miyabara, Elen H., Gopinath, Suchitra D., Carlig, Poppy M. M., Rando, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350665/
https://ncbi.nlm.nih.gov/pubmed/25520397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008411
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