Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate

Acamprosate supports abstinence in some alcohol-dependent subjects, yet predictors of response are unknown. To identify response biomarkers, we investigated associations of abstinence length with polymorphisms in candidate genes in glycine and glutamate neurotransmission pathways and genes previousl...

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Pubblicato in:Transl Psychiatry
Autori principali: Karpyak, V M, Biernacka, J M, Geske, J R, Jenkins, G D, Cunningham, J M, Rüegg, J, Kononenko, O, Leontovich, A A, Abulseoud, O A, Hall-Flavin, D K, Loukianova, L L, Schneekloth, T D, Skime, M K, Frank, J, Nöthen, M M, Rietschel, M, Kiefer, F, Mann, K F, Weinshilboum, R M, Frye, M A, Choi, D S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350512/
https://ncbi.nlm.nih.gov/pubmed/25290263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.103
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