TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response

We previously reported that SNPs near TSPAN5 were associated with plasma serotonin (5-HT) concentrations which were themselves associated with selective serotonin reuptake inhibitor treatment outcomes in patients with major depressive disorder (MDD). TSPAN5 SNPs were also associated with alcohol con...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Ho, Ming-Fen, Zhang, Cheng, Zhang, Lingxin, Wei, Lixuan, Zhou, Ying, Moon, Irene, Geske, Jennifer R., Choi, Doo-Sup, Biernacka, Joanna, Frye, Mark, Wen, Zhexing, Karpyak, Victor M., Li, Hu, Weinshilboum, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858703/
https://ncbi.nlm.nih.gov/pubmed/32753686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0855-9
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