Transcytosis in the continuous endothelium of the myocardial microvasculature is inhibited by N-ethylmaleimide.

In a murine heart perfusion system, we were able to "turn off" the transport of derivatized albumin [dinitrophenylated albumin (DNP-albumin)] from the perfusate to the tissue, by preperfusing the system with 1 mM N-ethylmaleimide (NEM) for 5 min at 37 degrees C, followed by a 5-min perfusion of DNP-...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Predescu, D, Horvat, R, Predescu, S, Palade, G E
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8159697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.8.3014
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