Transcytosis in the continuous endothelium of the myocardial microvasculature is inhibited by N-ethylmaleimide.
In a murine heart perfusion system, we were able to "turn off" the transport of derivatized albumin [dinitrophenylated albumin (DNP-albumin)] from the perfusate to the tissue, by preperfusing the system with 1 mM N-ethylmaleimide (NEM) for 5 min at 37 degrees C, followed by a 5-min perfusion of DNP-...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8159697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.8.3014 |
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