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The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila

Mating causes decreased life span in female Drosophila. Here we report that mifepristone blocked this effect, yielding life span increases up to +68%. Drug was fed to females after mating, in the absence of males, demonstrating function in females. Mifepristone did not increase life span of virgin f...

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Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Landis, Gary N., Salomon, Matthew P., Keroles, Daniel, Brookes, Nicholas, Sekimura, Troy, Tower, John
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350324/
https://ncbi.nlm.nih.gov/pubmed/25614682
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