Metabolic Signatures of Life Span Regulated by Mating, Sex Peptide, and Mifepristone/RU486 in Female Drosophila melanogaster

Mating and transfer of male sex peptide (SP), or transgenic expression of SP, causes inflammation and decreased life span in female Drosophila. Mifepristone rescues these effects, yielding dramatic increases in life span. Here targeted metabolomics data were integrated with further analysis of extan...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Landis, Gary N, Doherty, Devon V, Yen, Chia-An, Wang, Lu, Fan, Yang, Wang, Ina, Vroegop, Jonah, Wang, Tianyi, Wu, Jimmy, Patel, Palak, Lee, Shinwoo, Abdelmesieh, Mina, Shen, Jie, Promislow, Daniel E L, Curran, Sean P, Tower, John
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812429/
https://ncbi.nlm.nih.gov/pubmed/32648907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glaa164
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