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Multiphase modelling of the effect of fluid shear stress on cell yield and distribution in a hollow fibre membrane bioreactor

We present a simplified two-dimensional model of fluid flow, nutrient transport and cell distribution in a hollow fibre membrane bioreactor, with the aim of exploring how fluid flow can be used to control the distribution and yield of a cell population which is sensitive to both fluid shear stress a...

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Publicat a:Biomech Model Mechanobiol
Autors principals: Pearson, Natalie C., Waters, Sarah L., Oliver, James M., Shipley, Rebecca J.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349963/
https://ncbi.nlm.nih.gov/pubmed/25212097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-014-0611-7
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