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Optimising Cell Aggregate Expansion in a Perfused Hollow Fibre Bioreactor via Mathematical Modelling

The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell seeding strategy affect cell proliferation in the bi...

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Détails bibliographiques
Auteurs principaux: Chapman, Lloyd A. C., Shipley, Rebecca J., Whiteley, Jonathan P., Ellis, Marianne J., Byrne, Helen M., Waters, Sarah L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144904/
https://ncbi.nlm.nih.gov/pubmed/25157635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105813
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