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Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A(1) receptor-mediated transactivation of epidermal growth factor receptor

AIM: Paeoniflorin from Chinese herb Paeoniae Radix has been shown to ameliorate middle cerebral artery occlusion-induced ischemia in rats. The aim of this study was to investigate the mechanisms underlying the neuroprotective action of PF in cultured rat cortical neurons. METHODS: Primary cultured c...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zhong, Min, Song, Wan-ling, Xu, Ye-chun, Ye, Yang, Feng, Lin-yin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349929/
https://ncbi.nlm.nih.gov/pubmed/25661317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.154
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