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Adenosine A(1) receptor-mediated transactivation of the EGF receptor produces a neuroprotective effect on cortical neurons in vitro

AIM: To understand the mechanism of the transactivation of the epidermal growth factor receptor (EGFR) mediated by the adenosine A(1) receptor (A(1)R). METHODS: Primary cultured rat cortical neurons subjected to oxygen-glucose deprivation (OGD) and HEK293/A(1)R cells were treated with the A(1)R-spec...

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Detalhes bibliográficos
Main Authors: Xie, Ke-qiang, Zhang, Li-min, Cao, Yan, Zhu, Jun, Feng, Lin-yin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006641/
https://ncbi.nlm.nih.gov/pubmed/19574994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.80
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