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Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin

Centromere sequences are not conserved between species, and there is compelling evidence for epigenetic regulation of centromere identity, with location being dictated by the presence of chromatin containing the histone H3 variant CENP-A. Paradoxically, in most organisms CENP-A chromatin generally o...

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Pubblicato in:PLoS Genet
Autori principali: Catania, Sandra, Pidoux, Alison L., Allshire, Robin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349457/
https://ncbi.nlm.nih.gov/pubmed/25738810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004986
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