Deletion of scavenger receptor A gene in mice resulted in protection from septic shock and modulation of TLR4 signaling in isolated peritoneal macrophages

Scavenger receptor A (Sra), also known as macrophage scavenger receptor 1 (Msr1), is a surface glycoprotein preferentially present in macrophages that plays a primary role in innate immunity. Previous studies have shown that Sra is a modifier gene for the response to bacterial LPS in mice at the lev...

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Vydáno v:Innate Immun
Hlavní autoři: Drummond, Robert, Cauvi, David M, Hawisher, Dennis, Song, Donghuan, Niño, Diego F, Coimbra, Raul, Bickler, Stephen, De Maio, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349423/
https://ncbi.nlm.nih.gov/pubmed/22751446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425912449548
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