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Endoderm-specific deletion of Tbx1 reveals an FGF-independent role for Tbx1 in pharyngeal apparatus morphogenesis

BACKGROUND: The T-box transcription factor Tbx1, is essential for the normal development of multiple organ systems in the embryo. One of the most striking phenotypes in Tbx1−/− embryos is the failure of the caudal pharyngeal pouches to evaginate from the foregut endoderm. Despite considerable intere...

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Bibliografiske detaljer
Udgivet i:Dev Dyn
Main Authors: Jackson, Abigail, Kasah, Sahrunizam, Mansour, Suzanne L., Morrow, Bernice, Basson, M. Albert
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349409/
https://ncbi.nlm.nih.gov/pubmed/24812002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24147
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