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Cadherin-Catenin Complex Dissociation in Lobular Neoplasia of the Breast
BACKGROUND: E-cadherin (E-CD) inactivation with loss of E-CD-mediated cell adhesion is the hallmark of lesions of the lobular phenotype. E-CD is typically absent by immunohistochemistry in both lobular carcinoma in situ (LCIS) and invasive lobular lesions, suggesting it occurs early in the neoplasti...
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| Veröffentlicht in: | Breast Cancer Res Treat |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4349355/ https://ncbi.nlm.nih.gov/pubmed/22080244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1860-0 |
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