Cadherin-Catenin Complex Dissociation in Lobular Neoplasia of the Breast

BACKGROUND: E-cadherin (E-CD) inactivation with loss of E-CD-mediated cell adhesion is the hallmark of lesions of the lobular phenotype. E-CD is typically absent by immunohistochemistry in both lobular carcinoma in situ (LCIS) and invasive lobular lesions, suggesting it occurs early in the neoplasti...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Morrogh, Mary, Andrade, Victor P., Giri, Dilip, Sakr, Rita A., Paik, Wooyul, Qin, Li-Xuan, Arroyo, Crispinita D., Brogi, Edi, Morrow, Monica, King, Tari A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349355/
https://ncbi.nlm.nih.gov/pubmed/22080244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1860-0
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