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Cytogenetic heterogeneity negatively impacts outcomes in patients with acute myeloid leukemia

Clonal heterogeneity is a hallmark of malignant transformation. In acute myeloid leukemia, acquired cytogenetic abnormalities are important independent predictors of initial response to therapy, remission duration, and overall survival. However, whether the presence of multiple cytogenetically chara...

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Dettagli Bibliografici
Pubblicato in:Haematologica
Autori principali: Medeiros, Bruno C., Othus, Megan, Fang, Min, Appelbaum, Frederick R., Erba, Harry P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349271/
https://ncbi.nlm.nih.gov/pubmed/25527568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.117267
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