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Cytogenetic heterogeneity negatively impacts outcomes in patients with acute myeloid leukemia

Clonal heterogeneity is a hallmark of malignant transformation. In acute myeloid leukemia, acquired cytogenetic abnormalities are important independent predictors of initial response to therapy, remission duration, and overall survival. However, whether the presence of multiple cytogenetically chara...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Medeiros, Bruno C., Othus, Megan, Fang, Min, Appelbaum, Frederick R., Erba, Harry P.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349271/
https://ncbi.nlm.nih.gov/pubmed/25527568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.117267
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