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The Integrator complex controls the termination of transcription at diverse classes of gene targets

Complexes containing INTS3 and either NABP1 or NABP2 were initially characterized in DNA damage responses, but their biochemical function remained unknown. Using affinity purifications and HIV Integration targeting-sequencing (HIT-Seq), we find that these complexes are part of the Integrator complex...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Skaar, Jeffrey R, Ferris, Andrea L, Wu, Xiaolin, Saraf, Anita, Khanna, Kum Kum, Florens, Laurence, Washburn, Michael P, Hughes, Stephen H, Pagano, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349240/
https://ncbi.nlm.nih.gov/pubmed/25675981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.19
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