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An Enhanced Gene Targeting Toolkit for Drosophila: Golic+

Ends-out gene targeting allows seamless replacement of endogenous genes with engineered DNA fragments by homologous recombination, thus creating designer “genes” in the endogenous locus. Conventional gene targeting in Drosophila involves targeting with the preintegrated donor DNA in the larval primo...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Chen, Hui-Min, Huang, Yaling, Pfeiffer, Barret D., Yao, Xiaohao, Lee, Tzumin
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349064/
https://ncbi.nlm.nih.gov/pubmed/25555988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.173716
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