Sustained increase in α5GABA(A) receptor function impairs memory after anesthesia

Many patients who undergo general anesthesia and surgery experience cognitive dysfunction, particularly memory deficits that can persist for days to months. The mechanisms underlying this postoperative cognitive dysfunction in the adult brain remain poorly understood. Depression of brain function du...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Zurek, Agnieszka A., Yu, Jieying, Wang, Dian-Shi, Haffey, Sean C., Bridgwater, Erica M., Penna, Antonello, Lecker, Irene, Lei, Gang, Chang, Tom, Salter, Eric W.R., Orser, Beverley A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2014
Sujets:
Brief Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348961/
https://ncbi.nlm.nih.gov/pubmed/25365226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76669
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