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Detection of MGMT promoter methylation in glioblastoma using pyrosequencing

Recent clinical trials on patients with glioblastoma revealed that O6-Methylguanine-DNA methyltransferase (MGMT) methylation status significantly predicts patient’s response to alkylating agents. In this study, we sought to develop and validate a quantitative MGMT methylation assay using pyrosequenc...

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Foilsithe in:Int J Clin Exp Pathol
Main Authors: Xie, Hao, Tubbs, Raymond, Yang, Bin
Formáid: Artigo
Teanga:Inglês
Foilsithe: e-Century Publishing Corporation 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348884/
https://ncbi.nlm.nih.gov/pubmed/25755756
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