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Protected DNA strand displacement for enhanced single nucleotide discrimination in double-stranded DNA

Single nucleotide polymorphisms (SNPs) are a prime source of genetic diversity. Discriminating between different SNPs provides an enormous leap towards the better understanding of the uniqueness of biological systems. Here we report on a new approach for SNP discrimination using toehold-mediated DNA...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Khodakov, Dmitriy A., Khodakova, Anastasia S., Huang, David M., Linacre, Adrian, Ellis, Amanda V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348642/
https://ncbi.nlm.nih.gov/pubmed/25735213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08721
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