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Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy
Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disorder. It is caused by loss-of-function mutations in the dystrophin gene. Currently, there is no cure. A highly promising therapeutic strategy is to replace or repair the defective dystrophin gene by gene therapy. Numerous animal m...
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| Pubblicato in: | Dis Model Mech |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Limited
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348559/ https://ncbi.nlm.nih.gov/pubmed/25740330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.018424 |
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