Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase/Protein Kinase A Signaling Pathway

Mechanical stress that arises due to deformation of the extracellular matrix (ECM) either stretches or compresses cells. The cellular response to stretching has been actively studied. For example, stretching induces phosphorylation of the myosin regulatory light chain (MRLC) via the RhoA/RhoA-associ...

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Bibliographic Details
Published in:PLoS One
Main Authors: Takemoto, Kenji, Ishihara, Seiichiro, Mizutani, Takeomi, Kawabata, Kazushige, Haga, Hisashi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348516/
https://ncbi.nlm.nih.gov/pubmed/25734240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117937
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