Lipolysis of Visceral Adipocyte Triglyceride by Pancreatic Lipases Converts Mild Acute Pancreatitis to Severe Pancreatitis Independent of Necrosis and Inflammation

Visceral fat necrosis has been associated with severe acute pancreatitis (SAP) for over 100 years; however, its pathogenesis and role in SAP outcomes are poorly understood. Based on recent work suggesting that pancreatic fat lipolysis plays an important role in SAP, we evaluated the role of pancreat...

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Udgivet i:Am J Pathol
Main Authors: Patel, Krutika, Trivedi, Ram N., Durgampudi, Chandra, Noel, Pawan, Cline, Rachel A., DeLany, James P., Navina, Sarah, Singh, Vijay P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2015
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348470/
https://ncbi.nlm.nih.gov/pubmed/25579844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.11.019
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