Lipolysis of Visceral Adipocyte Triglyceride by Pancreatic Lipases Converts Mild Acute Pancreatitis to Severe Pancreatitis Independent of Necrosis and Inflammation

Visceral fat necrosis has been associated with severe acute pancreatitis (SAP) for over 100 years; however, its pathogenesis and role in SAP outcomes are poorly understood. Based on recent work suggesting that pancreatic fat lipolysis plays an important role in SAP, we evaluated the role of pancreat...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Patel, Krutika, Trivedi, Ram N., Durgampudi, Chandra, Noel, Pawan, Cline, Rachel A., DeLany, James P., Navina, Sarah, Singh, Vijay P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2015
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348470/
https://ncbi.nlm.nih.gov/pubmed/25579844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.11.019
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